Effect of Particle–Particle and RBC–Particle Interactions on Capture Efficiency of Magnetic Nanocarriers Under the Influence of a Nonuniform Magnetic Field

Abstract In this study, the capture efficiency (CE) of magnetic carrier particles at region interest (ROI) in a micro-vessel was investigated. A nonuniform field produced by Nd-Fe-B magnet applied to ROI. The particle–particle and red blood cell (RBC)–carrier particle interactions were taken into account. Other parameters including diameter, force, non-Newtonian behavior also considered. finite element method used solve governing equations. Four cases considered: (1) Newtonian without interaction forces, (2) with (3) (4) forces. results showed that for diameter 2000 nm, CE values case force 70% 53%, respectively. It found considering RBC–carrier all magnet–vessel distances, decreased, on average, nearly 19%. At distance 2.5 cm ( $$d=2.5\,\mathrm{cm}),$$ d = 2.5 cm ) , it seen 2 3 45%, representing maximum minimum values,